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Active Ingredient for 1ml
Lidocaine Hydrochloride 115.5mg
Excipients: Polyethylene glycol 400, propylene glycol, chlorhexidine digluconate, lavender essence, pure water.

Precoxin and its components

The active ingredient of Precoxin 10% Spray is lidocaine hydrochloride. Lidocaine is a substance generally used as a local anesthetic and works by blocking the transmission of signals at nerve endings. Thanks to this feature, Precoxin Spray containing lidocaine temporarily reduces the sensitivity in the area when applied topically on the male genital organ. This helps slow down premature ejaculation and allows the duration of sexual intercourse to be prolonged. Lidocaine blocks sodium channels, preventing nerve cells from transmitting pain signals. This helps reduce sensitivity on the surface of the genitals and thus prevent or delay premature ejaculation. Lidocaine hydrochloride is present in the Precoxin Spray formulation at a 10% concentration, which is an optimal concentration that allows the product to work effectively. This easy-to-use spray can be applied directly to specific areas of the genitals and is quickly absorbed, but its effect is temporary and lasts only for the time it is applied.

What is Premature Ejaculation?

What is Premature Ejaculation?

Premature ejaculation is one of the most common sexual dysfunctions in which ejaculation and orgasm occur before the desired time during sexual activity. It is called “premature ejaculation” and “ejaculation precox”.

It is a disease that affects 22.7% of men between the ages of 18-70 worldwide, and therefore the same percentage of couples.
Regardless of age, it affects approximately 1 in every 5 men worldwide. According to a comprehensive study conducted in Turkey, the incidence of the disease was found to be 20%.
Although premature ejaculation is one of the most commonly observed sexual dysfunctions in men under the age of 60, its diagnosis and treatment level is among the lowest among male diseases.
The sexual response in men has been defined as a cycle of physical changes consisting of 4 stages:
desire, arousal, orgasm (ejaculation), satisfaction
Sexual dysfunction in men usually occurs in one or more of the first 3 stages of the sexual response cycle. emerges. Although premature ejaculation was once thought to be only a psychological disorder, it is now known that the etiology of the disease depends on many reasons.

Behavioral therapies and drug treatments are used in the treatment of premature ejaculation. The type of treatment should be chosen according to the person and his/her partner.

Premature ejaculation is a disease and can be treated with medications recommended by the doctor; For this reason, it should not be forgotten that the products found on the websites will be harmful to health.

The only prescription drug in spray form used in the treatment of premature ejaculation is known as Prexocin. Prexocin eliminates the problem of premature ejaculation with medical methods and helps treat sexual anxiety disorder.

PRECOXIN contains lidocaine hydrochloride as the active ingredient. It is a white lavender scented spray. It is used to temporarily slow down premature ejaculation in men. Prepared as a 40 ml spray.

DO NOT USE PRECOXIN in the following situations
• You are hypersensitive (allergic) to PRECOXIN and amide type anesthetics,
• If there is an infection in the area where the spray will be applied and the infection is not treated,
/>• Do not use this product if you are not in the hospital and are taking medication for irregular heartbeat (such as amiodarone or sotalol).

USE PRECOXIN WITH CARE in the following situations. If:
• If you have a severe infection (sepsis) in which bacteria enter the blood, or if the mucosa in the area where the drug is applied is seriously damaged. In this case, caution should be exercised when applying PRECOXIN as there may be a risk of sudden absorption.
• If you have a known drug allergy. Be careful when using PRECOXIN. In patients allergic to paraaminobenzoic acid derivatives (such as procaine, tetracaine, benzocaine), sensitivity to lidocaine has not been observed.
• Effective and safe use of PRECOXIN is related to the appropriate dose. It is recommended that you use as small doses as possible. Pay attention to this especially in elderly patients, children and open
wound applications.
• If you have serious heart disease,
• Especially on large skin surfaces and especially under occlusion (closed dressing)
When applied, it may lead to heart rhythm disturbances, breathing difficulties, coma and even death.
• Avoid contact of PRECOXIN with eyes. Eye irritation has been observed and there is also the possibility of corneal irritation and potential abrasion due to loss of protective
reflexes. If eye
contact occurs, rinse your eyes immediately with water or saline and protect your eyes until sensation returns.
• If you are being treated with amiodarone to treat your irregular heartbeat. In this case,
you should be kept under close observation and an electrocardiogram should be considered.
• If you have an infection in the area where the spray will be applied. If this applies to you, your doctor may want you to use another medicine together with
• It should be determined before PRECOXIN treatment that you do not have a malignant tumor.
• PRECOXIN affects red blood cells It should be given only if it is a safer
alternative in patients with a disease (porphyria) that occurs due to the synthesis disorder of the substance that forms the structure of hemoglobin, comes in attacks and affects many
organ systems. Appropriate precautions should be taken for vulnerable patients.
If these warnings apply to you, even at any time in the past, please
consult your doctor.

Using PRECOXIN with food and drink.
Since PRECOXIN is not taken orally, it can be used with or without food.
Consult your doctor or pharmacist before using the medicine.
PRECOXIN, It should not be used if your partner is pregnant.
If you realize that you are pregnant during your treatment, consult your doctor or pharmacist immediately.
Consult your doctor or pharmacist before using the medicine.
br />Lidocaine passes into breast milk in small amounts. If your partner is breastfeeding, PRECOXIN
is not recommended for use during lactation.
Driving and using machines
It has no effect on the ability to drive and use machines.
PRECOXIN Important information about some excipients contained in PRECOXIN may cause skin irritation due to the propylene glycol it contains.

When used with the following drugs, an interaction may occur due to the absorption of lidocaine;
• Propranolol (a drug used in the treatment of hypertension): It may cause a decrease in the plasma clearance of lidocaine.
• Cimetidine ( A drug used in the treatment of peptic ulcer): Lidocaine causes a decrease in plasma clearance.
• Antiarrhythmic products (Drugs used in the treatment of heart rhythm disorders): It causes an increase in lidocaine
4 /7
• Phenytoin and barbiturates (drugs used in the treatment of epilepsy)
Cause a decrease in the plasma level of lidocaine.
The specified interactions may be observed in long-term and repeated use in high doses.

br />When administered at recommended doses, no clinically significant interactions
have been reported.
If you are currently using or have recently used any prescription or non-prescription medication, please inform your doctor and pharmacist about them. Please give.

Instructions for proper use and dosage / application frequency:
PRECOXIN Spray is designed for external use only.
It is applied 10 minutes before sexual intercourse to create a local anesthetic effect on the male genital skin.
br />Application route and method:
Unless your doctor has recommended otherwise, you can use it as described below.
You can start by spraying 1-2 sprays on the head and body of the penis. Spraying should not be done more than 6
times. The applied spray is rubbed until it is completely absorbed through the penis skin. It should be washed after sexual intercourse. . The product should not be used for more than 3 months
without consulting a doctor.
Different Age Groups
Usage in Children:
Does not apply to children.< br />Elderly:
There is no specific information regarding its use in the elderly. However, it is not recommended for elderly patients.
Special use cases:
Liver failure:
If you have severe liver failure, this Report the situation to your doctor. In case of kidney failure, there is no need to change the dose of your medicine, but inform your doctor about this situation. If you have the impression that the effect of PRECOXIN is too strong or weak, consult your doctor. or talk to your pharmacist.
If you use more PRECOXIN than you should:
PRECOXIN is used topically. If used accidentally and in large amounts or swallowed accidentally, the patient should be induced to vomit or the stomach should be rinsed. Symptomatic supportive
treatment is applied.
If you have used more PRECOXIN than you should, talk to a doctor or pharmacist.

You are not expected to experience any effects when you stop using PRECOXIN. If you suspect any
effects, consult your doctor.

Like all medicines, side
effects may occur in people who are sensitive to the substances contained in PRECOXIN.
If one of the following occurs, stop using PRECOXIN and immediately inform your
doctor or the nearest go to the emergency department of the hospital >• Severe itching accompanied by small blisters on the skin
These are very serious side effects. If you have this side effect, it means that you have
serious allergy to PRECOXIN.
You may need urgent medical intervention or hospitalization.
The side effects of PRECOXIN are similar to those of other amide type local anesthetics. similar effects. These
side effects are generally dose-dependent and may occur due to an increase in the amount passed into the blood in case of high dose administration or if the drug is absorbed faster than necessary. In addition,
side effects due to hypersensitivity, idiosyncrasy (sensitivity reactions of unknown cause) and decreased tolerance
may also occur. Serious side effects usually affect the whole body(systemic). These side effects may include nervousness, dizziness, visual disturbances, tremor, seizure(convulsion).
Side effects are described as shown in the following categories:
• Very common: at least 1 in 10 patients may experience
• Common: It can be seen in less than 1 in 10 patients, but it can be seen in more than 1 in 100 patients.
• Uncommon: It can be seen in less than 1 in 100 patients, but it can be seen in more than 1 in 1,000 patients.
• Rare: 1,000. It may occur in less than 1 in 10,000 patients, but may occur in more than 1 in 10,000 patients.
• Very rare: It may occur in less than 1 in 10,000 patients.
• Unknown: Cannot be estimated from the available data.
Uncommon: After long-term topical use Hypersensitivity may occur.
Common: Skin irritation, redness, itching or rash
Corneal irritation has been observed after accidental eye contact.
If you experience any side effects not mentioned in this leaflet
Inform your doctor or pharmacist.
Reporting side effects
If any side effects occur, whether listed in the instructions for use or not, talk to your doctor, pharmacist or nurse. Additionally, you can report any side effects you encounter to the Turkish Pharmacovigilance Center (TÜFAM) by clicking on the ‘Drug side effect notification) icon on the website or by calling 0 800
314 00 08 side effect reporting line.
Report. By reporting any side effects that occur, you will contribute to gaining more information about the
safety of the medicine you are using.

Keep PRECOXIN out of sight or reach of children and in its packaging.
Keep it at room temperatures below 25ºC and in its original packaging.
Use in accordance with the expiration date.
Do not throw away expired or unused medicines!
Give it to the collection system specified by the Ministry of Environment and Urbanization.
Do not use PRECOXIN after the expiration date on the packaging.
If you notice any defects in the product and/or its packaging, remove PRECOXIN. Do not use.

During our operational period of over forty years, we have experienced rapid changes and developments in medical technology both globally and in our country. In this process, Aymed Pharma has offered its experience and knowledge to the service of the medical world in our country.


Head Office

Ehlibeyt Mah. 1242. Cad. No:18/14 Aykon Plaza 06520 Balgat/ANKARA

Production Facility

Malıköy, Başkent OSB 18.Cd. No:16 06909 Sincan/ANKARA

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